Endocrine Abstracts

Objectives: Patients with acquired growth hormone (GH) deficiency secondary to hypopituitarism, have a significant increased risk of cardiovascular events. However, variable data of the effects of GH replacement and its benefits reducing such risk, is available. The aim of this study was to determine the impact of 0.4 milligrams of GH on cardiovascular markers in severe GH deficient adults with hypopituitarism.Methods: A total of 17 patients (10 males an...

Objectives: Conflicting data of the benefits of GH replacement improving psychological and physical well being is available, though open GH studies generally agree on an overall improvement. For growth hormone deficient patients to continue on therapy after evaluation there should be a 7 point improvement in their QoL-AGHDA, as documented in the NICE guidelines. The aim of this study was to determine the impact of 0.4 mg of GH on QoL in severe GH deficient patients in a double...

The Royal College of Physicians guidelines (2007) on follow-up post radioiodine therapy for hyperthyroidism recommend thyroid function monitoring around weeks 6, 12, 26, 39, 52 and yearly thereafter in stable patients. We retrospectively analyzed data from 91 patients given radioiodine in 2005 who were followed-up locally comparing our practice with these standards. Fifteen percent of patients were lost to follow-up before year one with 40% of these not having their thyroid fu...